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ACC

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ACC

结构式 货号 产品名称 CAS号
Clesacostat 结构式
 BCP39030 Clesacostat 1370448-25-1
Clesacostat is a potent and selective ACC inhibitor (hACC1 IC50 = 13nM; hACC@ IC50 = 9 nM).
Firsocostat (S enantiomer) 结构式
 BCP37635 Firsocostat (S enantiomer) ND-630S
Firsocostat S enantiomer is the less active S enantiomer of Firsocostat.
Soraphen A 结构式
 BCP25039 Soraphen A 122547-72-2
Soraphen A inhibits the acetyl-CoA carboxylase of fungi necessary for fatty acid synthesis .
Olumacostat glasaretil 结构式
 BCP25136 Olumacostat glasaretil 1261491-89-7
Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC).
CP 640186 结构式
 BCP09761 CP 640186 591778-68-6
CP-640186 is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively; with improved metabolic stability vs CP-610431.
CP-640186 hydrochloride 结构式
 BCP18564 CP-640186 hydrochloride 591778-70-0
CP-640186 Hcl is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively; with improved metabolic stability vs CP-610431.
PF05175157 结构式
 BCP25103 PF05175157 1301214-47-0
PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively.
TOFA 结构式
 BCP20578 TOFA 54857-86-2
TOFA (RMI14514;MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA ).
ND-646 结构式
 BCP29105 ND-646 1434639-57-2
ND-646 is an orally bioavailable and steric inhibitor of acetyl-CoA carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively.
ND-630 结构式
 BCP20893 ND-630 1434635-54-7
ND-630, also known as GS-0976 and NDI-010976, is a potent ACC inhibitor.
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