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TGF β/Smad

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TGF β/Smad

结构式 货号 产品名称 CAS号
HS-243 结构式
 BCP39678 HS-243 848249-10-5
HS-243 is an inhibitor of transforming growth factor-​beta kinase.
Halofuginone Hydrobromide 结构式
 BCP19376 常山酮氢溴酸盐 64924-67-0
Halofuginone Hydrobromide is a potent prolyl-tRNA synthetase inhibitor.
Chebulinic acid 结构式
 BCP09990 诃子林鞣酸 18942-26-2
Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity.
Halofuginone 结构式
 BCP07016 常山酮 55837-20-2
Halofuginone is a plant derivative that has been shown to inhibit Th17 differentiation, and recently tested as a potential immunosuppressant.
Halofuginone lactate 结构式
 BCP18878 常山酮内酯 82186-71-8
Halofuginone is the competitively inhibitor of prolyl-tRNA synthetase with Ki of 18.3 nM.
Halofuginone Hydrochloride 结构式
 BCP19375 盐酸卤夫酮;常山酮盐酸盐 1217623-74-9
Halofuginone is the competitively inhibitor of prolyl-tRNA synthetase with Ki of 18.3 nM.
Kartogenin 结构式
 BCP09135 Kartogenin 4727-31-5
Kartogenin(KGN) is a small molecule stimulator of chondrogenesis; promotes chondrocyte differentiation(EC50=100 nM) and binds to filamin A.
SIS3 HCl 结构式
 BCP19304 SIS3 HCl 521984-48-5
SIS3 is a potent and selective inhibitor of Smad3. a potent regulator of the human Nox4 promoter.
Pirfenidone 结构式
 BCP04473 吡非尼酮 53179-13-8
Pirfenidone leads to a reduction of TGF-β2 mRNA levels and of the mature TGF-β2 protein due to decreased expression and direct inhibition of the TGF-β pro-protein convertase furin.
GW788388 结构式
 BCP04559 GW788388 452342-67-5
GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, also inhibits TGF-β type II receptor and activin type II receptor activities, but does not inhibit BMP type II receptor.
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