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Beta catenin

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Beta catenin

结构式 货号 产品名称 CAS号
β-catenin-IN-2 结构式
 BCP48537 β-catenin-IN-2 1458664-10-2
β-catenin-IN-2 is a potent β-catenin inhibitor, compound H1B1, extracted from patent US20150374662A1.
LF3 结构式
 BCP45492 LF3 664969-54-4
LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 with an IC50 less than 2 μM.
β-catenin/CBP-IN-1 结构式
 BCP44122 β-catenin/CBP-IN-1 1198780-38-9
β-catenin/CBP-IN-1 (CBP/β-catenin inhibitor) is a potent and selective CBP/β-catenin inhibitor, extracted from the patent WO2014092154A1.
IWP-4 结构式
 BCP43694 IWP-4 686772-17-8
IWP-4 is a novel potent inhibitor of Wnt/β-catenin signaling.
CWP232228 sodium 结构式
 BCP43357 CWP232228 sodium 1144044-02-9
CWP232228 is a novel Wnt/β-Catenin inhibitor.
G244-LM 结构式
 BCP37837 G244-LM 1563007-08-8
G244-LM is a potent and specific small-molecule tankyrase inhibitors, which reduces Wnt/β-catenin signaling by preventing poly(ADP-ribosyl)ation-dependent AXIN degradation, thereby promoting β-catenin destabilization.
NRX-252262 结构式
 BCP36626 NRX-252262 2438637-61-5
NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation, with an EC50 of 3.8 nM.
C-82 结构式
 BCP35612 C-82 1422253-37-9
C-82 is a second-generation specific CBP/β-catenin antagonist, which inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.
KY1220 结构式
 BCP34008 KY1220 292168-79-7
KY1220 is a small molecule that simultaneously degrades β-catenin and Ras by inhibition of the Wnt/β-catenin pathway.
Tegatrabetan 结构式
 BCP32893 Tegatrabetan 1227637-23-1
Tegatrabetan is a β-Catenin antagonist. Tegatrabetan disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1).
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