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PDK

结构式 货号 产品名称 CAS号
PS210 结构式
 BCP37870 PS210 1221962-86-2
PS210 is a substrate-selective inhibitor of protein kinase PDK1.
UCN-01 结构式
 BCP14345 UCN-01 112953-11-4
UCN-01 (7-hydroxystaurosporine) acts as an inhibitor against many phosphokinases, such as the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases.
PDK1 inhibitor2 结构式
 BCP16225 PDK1 抑制剂2 850717-64-5
BX517 is a potent and selective inhibitor of PDK1 with IC50 of 6 nM.
GSK 2334470 结构式
 BCP08386 GSK 2334470 1227911-45-6
Potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM).
BAG956 结构式
 BCP01894 BAG956 853910-02-8
NVP-BAG956(BAG 956) is a potent, ATP-competitive and selective dual PI3K and PDK1 inhibitor in vitro and in vivo,with IC50 values to be 56, 444, 34, 117 and 240 nM for PI3K p110 alpha, beta, delta and gamma and PDK1 kinases, respectively.
BX795 结构式
 BCP01899 BX795 702675-74-9
BX795 is shown to be a specific and potent inhibitor of IκB kinase ε (IKKε), phosphoinositide 3-kinase 1 (PDK1), and TANK-binding kinase 1 (TBK1).
OSU-03012 结构式
 BCP01835 OSU-03012 742112-33-0
OSU03012; also known as AR12, is an orally available, targeted anti-cancer agent that has been shown in pre-clinical studies to inhibit PDK-1,OSU-03012 is a recently licensed novel derivative of the cyclooxygenase-2 (COX-2) inhibitor celecoxib .
BX-912 结构式
 BCP01898 BX-912 702674-56-4
BX-912 is a inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1).
PDK1 inhibitor 结构式
 BCP06483 PDK1 抑制剂 1001409-50-2
PDK1 inhibitor is a phosphoinositide-dependent kinase-1 (PDK1) inhibitor.
PS 48 结构式
 BCP08452 PS 48 1180676-32-7
Phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 μM). Binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site.
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