来法莫林新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP24164CAS号：1061337-51-6纯度：98%

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CAS号	1061337-51-6	货号	BCP24164
关联产品	1350636-82-6（醋酸来法莫林）
中文名	来法莫林
英文名	Lefamulin
中文别名
英文别名	BC-3781;BC 3781;BC3781;
SMILES	CC1CCC23CCC(=O)C2C1(C(CC(C(C3C)O)(C)C=C)OC(=O)CSC4CCC(CC4O)N)C
化学名称
分子式	C27H43NO5S	分子量	493.7
纯度	98%	配送	惯例下常温包邮
产品描述	Lefamulin is a semi-synthetic compound that inhibits the synthesis of bacterial protein, which is required for bacteria to grow. Lefamulin acts by binding to the peptidyl transferase center, or PTC, on the bacterial ribosome in such a way that it interferes with the interaction of protein production at two key sites known as the “A” site and the “P” site, resulting in the inhibition of bacterial proteins and the cessation of bacterial growth. Lefamulin’s binding occurs with high affinity, high specificity and at molecular sites that are different than other antibiotic classes. Lefamulin exhibited MIC50 and MIC90 values of 0.12 and 0.25 μg/ml, respectively, against the entire collection (n = 822). Similar results were obtained for lefamulin against each of the most common serotypes as well as against multidrug-resistant isolates and strains that are nonsusceptible to ceftriaxone or erythromycin. Lefamulin may be useful for the treatment of community-acquired respiratory tract infections.

来法莫林 新