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Lenrispodun 结构式

Lenrispodun

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货号 :BCP16186CAS号 :1160521-50-5纯度:98%
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  • 基本信息与产品描述
CAS号 1160521-50-5 货号 BCP16186
关联产品 1642303-38-5(Lenrispodun phosphate)
中文名 Lenrispodun
英文名 Lenrispodun
中文别名
英文别名 ITI-214; ITI 214; ITI214; PDE1-IN-1;PDE4 (R)-(-)-Rolipram;
SMILES CN1C(=O)C2=C(N(N=C2N3C1=NC4C3CCC4)CC5=CC=C(C=C5)C6=NC(=CC=C6)F)NC7=CC=CC=C7
化学名称
分子式 C29H26FN7O 分子量 507.56
纯度 98% 配送 惯例下常温包邮
产品描述 ITI-214 is an orally active, potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases. ITI-214 exhibited picomolar inhibitory potency for PDE1, demonstrated excellent selectivity against all other PDE families, and showed good efficacy in vivo. Currently, this investigational new drug is in Phase I clinical development and being considered for the treatment of several indications including cognitive deficits associated with schizophrenia and Alzheimer's disease, movement disorders, attention deficit and hyperactivity disorders, and other CNS and non-CNS disorders.
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