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CAS号 | 122111-03-9 | 货号 | BCP04160 |
中文名 | 盐酸吉西他滨 | ||
英文名 | Gemcitabine hydrochloride | ||
中文别名 | 盐酸吉西他宾;吉西他宾盐酸盐; | ||
英文别名 | Gemcitabine HCl; LY188011 hydrochloride;LY 188011 hydrochloride;LY-188011 hydrochloride; | ||
SMILES | |||
化学名称 | |||
分子式 | C9H12ClF2N3O4 | 分子量 | 299.66 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Gemcitabine induced NF-κB activity in BxPC-3, PANC-1, and MIA PaCa-2 cells and decreased the level of the NF-κB inhibitor IκBα in BxPC-3 and PANC-1 cells. Treatment of BxPC-3 cells with low dose Gemcitabine for 48 hours results in a dose-dependent increase in NF-κB binding. In contrast, NF-κB DNA binding is decreased in BxPC-3 cells treated with the higher Gemcitabine doses for 48 h; however, 24-h treatment with these higher doses increases NF-κB binding in BxPC-3 cells. |
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