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CAS号 | 1227637-23-1 | 货号 | BCP32893 |
中文名 | Tegatrabetan | ||
英文名 | Tegatrabetan | ||
中文别名 | |||
英文别名 | BC2059; BC-2059; BC 2059;Tegavivint; | ||
SMILES | CC1CC(CN(C1)S(=O)(=O)C2=CC3=C(C=C2)C(=C4C=CC(=CC4=C3N=O)S(=O)(=O)N5CC(CC(C5)C)C)NO)C | ||
化学名称 | |||
分子式 | C28H36N4O6S2 | 分子量 | 588.74 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Tegatrabetan is an orally bioavailable and potent β-catenin inhibitor. BC2059 potently induces apoptosis as a single agent and in combination with bortezomib in multiple myeloma. BC2059 induced apoptosis in 10/10 genetically heterogeneous human myeloma cell lines (HMCL) treated with dosages ranging from 50-500nM. |
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