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CAS号 | 1233855-46-3 | 货号 | BCP29970 |
中文名 | BIA10-2474 | ||
英文名 | BIA10-2474 | ||
中文别名 | |||
英文别名 | BIA 10-2474; BIA-10-2474; | ||
SMILES | CN(C1CCCCC1)C(=O)N2C=C(N=C2)C3=C[N+](=CC=C3)[O-] | ||
化学名称 | |||
分子式 | C16H20N4O2 | 分子量 | 300.36 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | BIA10-2474 is a long-acting reversible inhibitor of fatty acid amide hydrolase (FAAH) that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (that is, the rest of the body other than the brain and spinal cord). BIA 10-2474 interacts with the human endocannabinoid system. BIA 10-2474 was in development for the treatment of a range of different medical conditions from anxiety to Parkinson's disease, also for the treatment of chronic pain of multiple sclerosis, cancer, hypertension or the treatment of obesity. A clinical trial with this drug was underway in Rennes, France, in which severe adverse events occurred in January 2016 affecting 5 patients, including leading to the death of one. |
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