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| CAS号 | 1239908-20-3 | 货号 | BCP16600 |
| 中文名 | 枸橼酸艾莎佐米 | ||
| 英文名 | Ixazomib citrate | ||
| 中文别名 | 伊莎佐米柠檬酸盐; | ||
| 英文别名 | MLN9708; MLN-9708; MLN 9708;Ixazomib-prodrug; | ||
| SMILES | O=C(O)CC1(CC(O)=O)OB([C@@H](NC(CNC(C2=CC(Cl)=CC=C2Cl)=O)=O)CC(C)C)OC1=O | ||
| 化学名称 | |||
| 分子式 | C20H23BCl2N2O9 | 分子量 | 517.119 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | MLN9708, also known as ixazomib citrate, is a prodrug of Ixazomib (MMLN-2238). MLN9708 is an orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity. MLN9708, after hydrolyzing to pharmacologically active MLN2238 (ixazomib), is a next-generation proteasome inhibitor with demonstrated preclinical and clinical antimyeloma activity. MLN9708, compared with bortezomib, has improved pharmacokinetics, pharmacodynamics, and antitumor activity in preclinical studies. | ||
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