Denifanstat 新

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货号：BCP30428CAS号：1399177-37-7纯度：98%

规格	价格(CNY)	是否现货	购买咨询
5.00 mg	￥2000.00	In-stock	购买咨询
25.00 mg	￥6000.00	In-stock	购买咨询

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CAS号	1399177-37-7	货号	BCP30428
中文名	Denifanstat
英文名	Denifanstat
中文别名
英文别名	TVB-2640;TVB2640; TVB 2640;FASN-IN-2; ASC-40; ASC40; ASC 40;
SMILES	N#CC1=CC=C(C2CCN(C(C3=CC(C4=NN=C(C)N4)=C(C5CCC5)C=C3C)=O)CC2)C=C1
化学名称
分子式	C27H29N5O	分子量	439.56
纯度	98%	配送	惯例下常温包邮
产品描述	TVB-2640 is an orally bioavailable fatty acid synthase (FASN) inhibitor, with potential antineoplastic activity. Upon administration, TVB-2640 binds to and blocks FASN, which prevents the synthesis of palmitate needed for tumor cell growth and survival. This leads to a reduction in cell signaling, an induction of tumor cell apoptosis and the inhibition of cell proliferation in susceptible tumor cells. FASN, an enzyme responsible for the de novo synthesis of palmitic acid, is overexpressed in tumor cells and plays a key role in tumor metabolism, lipid signaling, tumor cell survival and drug resistance; tumor cells are dependent on increased fatty acid production for their enhanced metabolic needs and rapid growth.