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PRI-724 结构式

PRI-724

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货号 :BCP32677CAS号 :1422253-38-0纯度:98%
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  • 基本信息与产品描述
CAS号 1422253-38-0 货号 BCP32677
关联产品 780757-88-2(ICG-001) 847591-62-2(ICG-001)
中文名 PRI-724
英文名 PRI-724
中文别名
英文别名 PRI724; PRI 724; C-82 prodrug; ICG-001 analog; ICG001 analog; ICG 001 analog;
SMILES CC1C2N(C(C(=O)N1CC3=CC=CC4=C3N=CC=C4)CC5=CC=C(C=C5)OP(=O)(O)O)C(=O)CN(N2C(=O)NCC6=CC=CC=C6)C
化学名称
分子式 C33H35N6O7P 分子量 658.65
纯度 98% 配送 惯例下常温包邮
产品描述 PRI-724 is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity. Wnt signaling pathway inhibitor PRI-724 specifically inhibits the recruiting of beta-catenin with its coactivator CBP (the binding protein of the cAMP response element-binding protein CREB); together with other transcription factors beta-catenin/CBP binds to WRE (Wnt-responsive element) and activates transcription of a wide range of target genes of Wnt/beta-catenin signaling.
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