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| CAS号 | 153653-30-6 | 货号 | BCP24840 |
| 中文名 | Dofequidar fumarate | ||
| 英文名 | Dofequidar fumarate | ||
| 中文别名 | |||
| 英文别名 | MS-209; MS 209; MS209; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C34H35N3O7 | 分子量 | 597.66 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Dofequidar fumarate(MS-209 fumarate), an orally active quinoline compound, has been reported to overcome MDR by inhibiting ABCB1/P-gp, ABCC1/MDR-associated protein 1, or both.Dofequidar, also known as MS-209, is a quinolone-derived sphingomyelin synthase inhibitor that blocks P-glycoprotein and multidrug resistance-associated protein-1, is under development by Schering for the potential treatment of multidrug resistant tumors. Dofequidar was found to sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export. | ||
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