瑞玛奈珠单抗新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP46102CAS号：1655501-53-3纯度：98%

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CAS号	1655501-53-3	货号	BCP46102
中文名	瑞玛奈珠单抗
英文名	Fremanezumab
中文别名
英文别名	LBR-101;PF-04427429;PF-4427429;RI-307;RN-307;RN307;TEV-48125;
SMILES
化学名称
分子式		分子量
纯度	98%	配送	惯例下常温包邮
产品描述	Fremanezumab (TEV-48125) is a humanised IgG2a monoclonal antibody targeting calcitonin gene-related peptide (CGRP), a peptide known to play a role in causing migraines. TEV-48125 was originally formulated as an intravenous agent, but has been re-formulated to allow sub-cutaneous administration. Anti-CGRP antibodies are being developed as an alternative to CGRP receptor antagonists (such as telcagepant) which have already been shown to effectively reduce migraine headache and inhibit neurogenic vasodilatation in humans, and validated the CGRP/CGPR pathway as a target for the acute and preventive treatments of migraine. Anti-CGRP antibodies have the advantage of longer half-lives compared to small molecule antagonists and are expected to exhibit fewer toxicities attributed to off-target interactions, toxitities which have thwarted the development of CGRP receptor antagonists.

瑞玛奈珠单抗 新