Bexotegrast 新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP49211CAS号：2376257-44-0纯度：98%

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CAS号	2376257-44-0	货号	BCP49211
中文名	Bexotegrast
英文名	Bexotegrast
中文别名
英文别名	PLN-74809;PLN 74809;PLN74809;
SMILES	COCCN(CCCCC1=NC2=C(CCCN2)C=C1)CCC(C(=O)O)NC3=NC=NC4=CC=CC=C43
化学名称
分子式	C27H36N6O3	分子量	492.61
纯度	98%	配送	惯例下常温包邮
产品描述	Bexotegrast is a small-molecule that dually inhibits both αvβ6 and αvβ1 to treat both idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC). The compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and Pliant Therapeutics recently raised $100 million in Series C financing to support further clinical development of this compound. Phase 2a studies are currently evaluating PLN-74809 safety and efficacy for participants with IPF (NCT04396756)across 10 participating countries, and for participants with PSC (NCT04480840). In addition, the compound is also currently in Phase 2a trials (NCT04565249) for the treatment of COVID-19 related acute respiratory distress syndrome.