BLU-945 新
参考资料
仅供科学研究,不可用于个人用途。
规格 | 价格(CNY) | 是否现货 | 购买咨询 |
---|---|---|---|
10.00 mg | ¥880.00 | In-stock | 购买咨询 |
25.00 mg | ¥1320.00 | In-stock | 购买咨询 |
100.00 mg | ¥3700.00 | In-stock | 购买咨询 |
1.00 g | 询价 | In-stock | 购买咨询 |
10.00 g | 询价 | In-stock | 购买咨询 |
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CAS号 | 2660250-10-0 | 货号 | BCP45854 |
中文名 | BLU-945 | ||
英文名 | BLU-945 | ||
中文别名 | |||
英文别名 | BLU945;BLU 945; | ||
SMILES | CC1C(CN1C2=C3C=NC(=CC3=C(C=C2)C(C)C)NC4=NC(=NC=C4)N5CCC(C(C5)F)OC)CS(=O)(=O)C | ||
化学名称 | |||
分子式 | C28H37FN6O3S | 分子量 | 556.7 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | BLU-945 is a potent, selective, and orally available EGFR inhibitor that shows robust anti-tumor activity in osimertinib-resistant EGFR xenograft models.BLU-945 inhibits EGFRex19del/T790M/C797S, EGFRL858R/T790M/C797S, EGFRex19del/T790M, and EGFRL858R/T790M mutants with sub-nanomolar IC50 values in an enzyme assay with a >1000-fold window over EGFRWT enzyme activity. |
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