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CAS号 | 355151-12-1 | 货号 | BCP24086 |
中文名 | Rotigaptide | ||
英文名 | Rotigaptide | ||
中文别名 | |||
英文别名 | GAP-486; ZP-123; GAP486; ZP123; GAP 486; ZP 123; | ||
SMILES | CC(C(=O)NCC(=O)N)NC(=O)CNC(=O)C1CC(CN1C(=O)C2CCCN2C(=O)C(CC3=CC=C(C=C3)O)NC(=O)C)O | ||
化学名称 | |||
分子式 | C28H39N7O9 | 分子量 | 617.65 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Rotigaptide is a novel and specific modulator of connexin 43 (Cx43). Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability and has the potential for the investigation of cardiac arrhythmias-specifically atrial fibrillation. |
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