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CAS号 | 476181-74-5 | 货号 | BCP30499 |
中文名 | 戈利木单抗 | ||
英文名 | Golimumab | ||
中文别名 | |||
英文别名 | Simponi;CNTO 148;CNTO-148;CNTO148; | ||
SMILES | |||
化学名称 | |||
分子式 | C6530H10068N1752O2026S44 | 分子量 | 147 kg/mol |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Golimumab (CNTO 148) is a human monoclonal antibody which is used as an immunosuppressive drug. Golimumab targets tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory molecule and hence is a TNF inhibitor. Profound reduction in C-reactive protein (CRP) levels, interleukin (IL)-6, intercellaular adhesion molecules (ICAM)-1, matrix metalloproteinase (MMP)-3, and vascular endothelial growth factor (VEGF) demonstrates golimumab as an effective modulator of inflammatory markers and bone metabolism. |
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