嘌呤胺新热

参考资料仅供科学研究，不可用于个人用途。

货号：BCP03687CAS号：483367-10-8纯度：98%

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CAS号	483367-10-8	货号	BCP03687
中文名	嘌呤胺
英文名	Purmorphamine
中文别名
英文别名
SMILES	N1(C2CCCCC2)C=NC3=C(NC4=CC=C(N5CCOCC5)C=C4)N=C(OC6=C7C=CC=CC7=CC=C6)N=C13
化学名称
分子式	C31H32N6O2	分子量	520.63
纯度	98%	配送	惯例下常温包邮
产品描述	Purmorphamine is an activator of Smoothened, and blocks BODIPY-cyclopamine binding to Smo with IC50 of appr 1.5 μM and also is an inducer of osteoblast differentiation with EC50 of 1 μM.Purmorphamine is a Hedgehog agonist, which activates the Hedgehog pathway by targeting Smoothened. Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. Purmorphamine increases DARPP-32 differentiation in human striatal neural stem cells through the Hedgehog pathway. Purmorphamine enhances osteogenic activity of human osteoblasts derived from bone marrow mesenchymal cells. Hedgehog (Hh) signaling is an important regulator of embryonic patterning, tissue regeneration, stem cell renewal and cancer growth.

嘌呤胺 新 热