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CAS号 | 510-77-0 | 货号 | BCP12248 |
中文名 | 加兰他敏 | ||
英文名 | Galanthaminone | ||
中文别名 | 那维啶;那维定; | ||
英文别名 | (-)-Narwedine;Narwedin; 3-Deoxy-3-oxo-galanthamine; | ||
SMILES | |||
化学名称 | |||
分子式 | C17H19NO3 | 分子量 | 285.34 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Galanthaminone reduces the action of AChE and therefore tends to increase the concentration of acetylcholine in the brain. is also an allosteric ligand at nicotinic acetylcholine receptors. It has shown activity in modulating the nicotinic cholinergic receptors on cholinergic neurons to increase acetylcholine release. Absorption of galantamine is rapid and complete and shows linear pharmacokinetics. It is well absorbed with absolute oral bioavailability between 80 and 100%. It has a half-life of seven hours. Peak effect of inhibiting acetylcholinesterase was achieved about one hour after a single oral dose of 8 mg in some healthy volunteers. |
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