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瀚香生物(Biochempartner)的德拉马尼被文献引用
| CAS号 | 681492-22-8 | 货号 | BCP07838 |
| 中文名 | 德拉马尼 | ||
| 英文名 | Delamanid | ||
| 中文别名 | 迪拉马尼;地依麦迪; | ||
| 英文别名 | OPC-67683; OPC 67683; OPC67683; | ||
| SMILES | FC(F)(F)OC1=CC=C(OC2CCN(C3=CC=C(OC[C@@]4(C)CN5C(O4)=NC([N+]([O-])=O)=C5)C=C3)CC2)C=C1 | ||
| 化学名称 | |||
| 分子式 | C25H25F3N4O6 | 分子量 | 534.48 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Delamanid, also known as OPC-67683, is a drug for the treatment of multi-drug-resistant tuberculosis. It works by blocking the synthesis of mycolic acids in Mycobacterium tuberculosis, the organism which causes tuberculosis, thus destabilising its cell wall. The drug is approved in the EU. Delamanid inhibits the synthesis of mycolic acids, crucial component of the cell wall of the Mycobacterium tuberculosis complex. Delamanid is insoluble in water and its activity was proven in several in vitro and in vivo studies. Its bactericidal activity was demonstrated in individuals with drug-susceptible and drug-resistant tuberculosis (MDR- and XDR-TB). | ||
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