醋酸亮丙瑞林

参考资料仅供科学研究，不可用于个人用途。

货号：BCP02071CAS号：74381-53-6纯度：98%

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CAS号	74381-53-6	货号	BCP02071
中文名	醋酸亮丙瑞林
英文名	Leuprorelin acetate
中文别名
英文别名	Leuprorelin acetate;
SMILES
化学名称
分子式	C59H84N16O12.C2H4O2	分子量	1269.45
纯度	98%	配送	惯例下常温包邮
产品描述	By interrupting the normal pulsatile stimulation of, and thus desensitizing, the GnRH receptors, it indirectly downregulates the secretion of gonadotropins luteinizing hormone and follicle-stimulating hormone, leading to hypogonadism and thus a dramatic reduction in estradiol andtestosterone levels in both sexes. in vitro: The number of DNA 3'-end-labeled cells/cm2 in leiomyomas of control patients and in leiomyomas at the 2nd, 8th, 12th, and 16th weeks of Leuprolide Acetate treatment were at low levels. Testosterone, estradiol and progesterone were also reduced by LA, even though this reduction occurred for progesterone only at the highest LA dosage (10(-6)M; 606.0+/-114.3 ng/ml versus 1524.0+/-246.5 ng/ml; p=0.02). in vivo: Leuprolide acetate treatment decreases the severity of clinical signs of locomotion, induces a significantly greater body weight gain, increases the MBP and NFs expression, axonal area and cell infiltration in EAE animals. Leuprolide (200 and 300 microg kg(-1) s.c