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Tesevatinib 结构式

Tesevatinib

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP23438CAS号 :781613-23-8纯度:98%
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  • 基本信息与产品描述
CAS号 781613-23-8 货号 BCP23438
中文名 Tesevatinib
英文名 Tesevatinib
中文别名
英文别名 XL-647; XL 647; XL647; EXEL7647; EXEL-7647; EXEL7647; KD-019; KD019; KD 019;
SMILES CN1CC2CC(CC2C1)COC3=C(C=C4C(=C3)N=CN=C4NC5=C(C(=C(C=C5)Cl)Cl)F)OC
化学名称
分子式 C24H25Cl2FN4O2 分子量 490.13
纯度 98% 配送 惯例下常温包邮
产品描述 Tesevatinib, also known as XL647, EXEL-7647 and KD-019, is a n orally bioavailable small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. XL647 binds to and inhibits several tyrosine receptor kinases that play major roles in tumor cell proliferation and tumor vascularization, including epidermal growth factor receptor (EGFR; ERBB1), epidermal growth factor receptor 2 (HER2; ERBB2), vascular endothelial growth factor receptor (VEGFR), and ephrin B4 (EphB4). This may result in the inhibition of tumor growth and angiogenesis, and tumor regression.
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