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| CAS号 | 79617-96-2 | 货号 | BCP26219 |
| 中文名 | 舍曲林 | ||
| 英文名 | Sertraline | ||
| 中文别名 | |||
| 英文别名 | Sealdin; Adjuvin; Atruline; CP 51,974-1; Cp-51,974-1; CP 51,974; CP51,974; CP-51,974; Gladem; Tatig; Tresleen; Zoloft; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C17H17Cl2N | 分子量 | 306.23 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Sertraline is a selective serotonin uptake inhibitor that is used in the treatment of depression. Sertraline is primarily a serotonin reuptake inhibitor (SRI) with a binding affinity towards the serotonin transporter of Ki=2.8 nM or in that range. Sertraline is also a dopamine reuptake inhibitor, (<50 nmol/L). However, this is not considered a tight binding, and this action is only 10% of its potency as a monoamine reuptake inhibitor. It is a σ1 receptor agonist with 5% of its SRI potency, and an α1-adrenoreceptor antagonist with 1–10% of its SRI potency. | ||
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