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CAS号 | 86541-74-4 | 货号 | BCP27638 |
中文名 | 盐酸贝那普利 | ||
英文名 | Benazepril HCl | ||
中文别名 | |||
英文别名 | Benazepril hydrochloride;Lotension;CGS 14824A HCl;CGS-14824A;CGS14824A; | ||
SMILES | CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=CC=CC=C3N(C2=O)CC(=O)O.Cl | ||
化学名称 | |||
分子式 | C24H28N2O5.HCl | 分子量 | 460.95 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Benazepril Hydrochloride is the hydrochloride salt of benazepril, a carboxyl-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, benazepril is metabolized to its active form benazeprilat. Benazeprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II, resulting in vasodilation. Benazeprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. |
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