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| CAS号 | 865854-05-3 | 货号 | BCP06016 |
| 中文名 | Tideglusib | ||
| 英文名 | Tideglusib | ||
| 中文别名 | |||
| 英文别名 | NP-12;NP031112;NP 031112;NP-031112; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C19H14N2O2S | 分子量 | 334.39 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Tideglusib irreversibly inhibits GSK-3, reduces tau phosphorylation, and prevents apoptotic death in human neuroblastoma cells and murineprimary neurons.Tideglusib (2.5 μM) inhibits glutamate-induced glial activation as evidenced by decreased TNF-α and COX-2 expression in rat primary astrocyte or microglial cultures. Tideglusib (2.5 μM) also exerts a potent neuroprotective effect on cortical neurons from glutamate-induced excitotoxicity as evidenced by significant reduction in the number of Annexin-V-positive cells in rat primary astrocyte or microglial cultures. | ||
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