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CAS号 | 87081-35-4 | 货号 | BCP35974 |
中文名 | 来普霉素B | ||
英文名 | Leptomycin B | ||
中文别名 | 细霉素B; | ||
英文别名 | CI 940; LMB;Elactocin;Mantuamycin; | ||
SMILES | O=C(O)/C=C(C)/C[C@H](C)C(O)[C@H](C)C([C@H](C)/C=C(C)/C=C/C[C@@H](C)/C=C(CC)\C=C\[C@H]1[C@@H](C)C=CC(O1)=O)=O | ||
化学名称 | |||
分子式 | C33H48O6 | 分子量 | 540.74 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Leptomycin B is a potent inhibitor of the nuclear export of proteins. It directly blocks the interaction of CRM1 (exportin 1) with nuclear export signals (NES), preventing the export of a broad range of proteins. Leptomycin B reduces primary and acquired resistance of gefitinib in lung cancer cells. |
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