Ifebemtinib 新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP45896CAS号：1227948-82-4纯度：98%

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CAS号	1227948-82-4	货号	BCP45896
中文名	Ifebemtinib
英文名	Ifebemtinib
中文别名
英文别名	BI853520;IN10018;BI-853520;IN-10018;BI8 53520;IN 10018;
SMILES	CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2F)NC3=NC=C(C(=N3)OC4=CC=CC5=C4C(=O)N(C5)C)C(F)(F)F)OC
化学名称
分子式	C28H28F4N6O4	分子量	588.55
纯度	98%	配送	惯例下常温包邮
产品描述	Protein Tyrosine Kinase 2 Inhibitor IN10018 is an orally bioavailable inhibitor of the non-receptor, cytoplasmic tyrosine kinase protein tyrosine kinase 2 (focal adhesion kinase 1; FAK1; FAK: PTK2) with potential antineoplastic activity. Upon oral administration, IN10018 targets and inhibits, in an adenosine triphosphate (ATP)-competitive manner, PTK2. This prevents PTK2-mediated downstream signaling and inhibits migration, proliferation, invasion, and survival in PTK2-overexpressing tumor cells. The cytoplasmic tyrosine kinase PTK2, a signal transducer for integrins overexpressed in various tumor cell types, is involved in tumor cell invasion, migration and proliferation.