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| CAS号 | 150208-28-9 | 货号 | BCP28878 |
| 中文名 | BD1063 | ||
| 英文名 | BD1063 | ||
| 中文别名 | |||
| 英文别名 | BD 1063; BD-1063;206996-13-6(2HCl);BD-1063 Dihydrochloride; BD1063 Dihydrochloride;BD 1063 2HCl; | ||
| SMILES | CN1CCN(CCC2=CC=C(Cl)C(Cl)=C2)CC1 | ||
| 化学名称 | |||
| 分子式 | C13H18Cl2N2 | 分子量 | 273.20 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | BD1063 is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 9 ± 1 nM for the sigma-1 receptor and more than 49 times selectivity over the sigma-2 receptor. Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with BD1063 significantly decreases the convulsivity and lethality of cocaine. In other animal studies, BD1063 blocks the effects of MDMA, and reduces alcohol intake in rodent models of alcoholism. | ||
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