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CAS号 | 1532533-75-7 | 货号 | BCP24681 |
中文名 | Umbralisib sulfate | ||
英文名 | Umbralisib sulfate | ||
中文别名 | |||
英文别名 | TGR-1202 sulfate; RP-5264 sulfate; | ||
SMILES | CC(C)OC1=C(C=C(C=C1)C2=NN(C3=NC=NC(=C23)N)C(C)C4=C(C(=O)C5=C(O4)C=CC(=C5)F)C6=CC(=CC=C6)F)F.OS(=O)(=O)O | ||
化学名称 | |||
分子式 | C31H26F3N5O7S | 分子量 | 669.63 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Umbralisib sulfate is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib sulfate exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib sulfate can be used for haematological malignancies reseach. |
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