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CAS号 | 155148-31-5 | 货号 | BCP11743 |
关联产品 | 110078-46-1(普乐沙福) 155148-32-6(普乐沙福八氢溴酸盐) | ||
中文名 | 八盐酸普乐沙福 | ||
英文名 | Plerixafor octahydrochloride | ||
中文别名 | 普乐沙福八盐酸盐; | ||
英文别名 | Plerixafor 8HCl;AMD3100 8HCl;JM3100 8HCl;SID791 8HCl;AMD3100; AMD-3100; AMD 3100; JM 3100; JM3100; JM-3100; SDZ-SID-791; | ||
SMILES | C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3.Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl | ||
化学名称 | |||
分子式 | C28H62Cl8N8 | 分子量 | 794.47 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Plerixafor octahydrochloride is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.Plerixafor, also known as AMD3100, is a bicyclam with hematopoietic stem cell-mobilizing activity. Plerixafor blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow and HSC movement into the peripheral circulation. |
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