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Amiodarone 结构式

胺碘酮

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP35085CAS号 :1951-25-3纯度:98%
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  • 基本信息与产品描述
CAS号 1951-25-3 货号 BCP35085
中文名 胺碘酮
英文名 Amiodarone
中文别名 安律酮;
英文别名 Cordarone; Amiodarona; Amiodaronum;
SMILES CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I
化学名称
分子式 C25H29I2NO3 分子量 645.31
纯度 98% 配送 惯例下常温包邮
产品描述 Amiodarone is categorized as a class III antiarrhythmic agent, and prolongs phase 3 of the cardiac action potential, the repolarization phase where there is normally decreased calcium permeability and increased potassium permeability. It has numerous other effects however, including actions that are similar to those of antiarrhythmic classes Ia, II, and IV. Amiodarone shows beta blocker-like and calcium channel blocker-like actions on the SA and AV nodes, increases the refractory period via sodium- and potassium-channel effects, and slows intra-cardiac conduction of the cardiac action potential, via sodium-channel effects.Amiodarone chemically resembles thyroxine (thyroid hormone), and its binding to the nuclear thyroid receptor might contribute to some of its pharmacologic and toxic actions.
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