LYN-1604

参考资料仅供科学研究，不可用于个人用途。

货号：BCP28888CAS号：2088939-99-3纯度：98%

规格	价格(CNY)	是否现货	购买咨询
25.00 mg	￥2800.00	In-stock	购买咨询
50.00 mg	￥3900.00	In-stock	购买咨询

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CAS号	2088939-99-3	货号	BCP28888
关联产品	LYN-1604HLC（LYN-1604 hydrochloride） 2310109-38-5（LYN-1604 dihydrochloride）
中文名	LYN-1604
英文名	LYN-1604
中文别名
英文别名	LYN 1604; LYN1604;
SMILES
化学名称
分子式	C33H43Cl2N3O2	分子量	584.62
纯度	98%	配送	惯例下常温包邮
产品描述	LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis. LYN-1604 could induce cell death, associated with autophagy by the ULK complex (ULK1-mATG13-FIP200-ATG101) in MDA-MB-231 cells. To further explore LYN-1604-induced autophagic mechanisms, we found some potential ULK1 interactors, such as ATF3, RAD21, and caspase3, by performing comparative microarray analysis. LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis. LYN-1604 has potential for good therapeutic effects on TNBC by targeting ULK1-modulated cell death in vivo; thus making this ULK1 agonist a novel potential small-molecule drug candidate for future TNBC therapy.