索贝罗姆新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP23779CAS号：211110-63-3纯度：98%

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CAS号	211110-63-3	货号	BCP23779
中文名	索贝罗姆
英文名	Sobetirome
中文别名	索贝替罗姆;
英文别名	GC-1; GC1; GC 1; QRX-431; QRX 431; QRX431;
SMILES	O=C(O)COC1=CC(C)=C(CC2=CC=C(O)C(C(C)C)=C2)C(C)=C1
化学名称
分子式	C20H24O4	分子量	328.4
纯度	98%	配送	惯例下常温包邮
产品描述	Sobetirome, also known as GC-1 and QRX-431, is a hyroid hormone beta-receptor agonist. Sobetirome inhibits proliferation but induces differentiation and TR beta mRNA expression in mouse and rat osteoblast-like cells. Sobetirome selectively binds to and activates TRbeta over TRalpha and this receptor selectivity led to the hypothesis that sobetirome would lower cholesterol through activation of liver TRbeta without stimulating cardiac function through TRalpha activation in the heart. The tissue selective thyromimetic properties of sobetirome have been demonstrated in numerous animal models, which led to its clinical development as a novel cholesterol-lowering agent.

索贝罗姆 新