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CAS号 | 254737-29-6 | 货号 | BCP29740 |
中文名 | 2-MPPA | ||
英文名 | 2-MPPA | ||
中文别名 | |||
英文别名 | 2-(3-mercaptopropyl)pentanedioic acid;2-(3-sulfanylpropyl)pentanedioic acid; | ||
SMILES | C(CC(CCC(=O)O)C(=O)O)CS | ||
化学名称 | |||
分子式 | C8H14O4S | 分子量 | 206.26 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | 2-MPPA is a selective glutamate carboxypeptidase II (GCP II) inhibitor (IC50 = 90 nM). Selective for GCP II over NMDA, kainate and AMPA glutamate receptors and MMP-1, -2, -3, -7, -9, ACE and NEP metalloproteases. Antinociceptive in a rat model of neuropathic pain and protects against motor neuron death in familial amyotrophic lateral sclerosis mice. Orally bioavailable. |
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