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Fosaprepitant dimeglumine 结构式

福沙吡坦二甲葡胺

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货号 :BCP05167CAS号 :265121-04-8纯度:98%
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  • 基本信息与产品描述
CAS号 265121-04-8 货号 BCP05167
关联产品 172673-20-0(福沙吡坦)
中文名 福沙吡坦二甲葡胺
英文名 Fosaprepitant dimeglumine
中文别名
英文别名 MK-0517 dimeglumine; MK0517 dimeglumine; MK 0517 dimeglumine;
SMILES CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F.CNCC(C(C(C(CO)O)O)O)O.CNCC(C(C(C(CO)O)O)O)O
化学名称
分子式 C23H22F7N4O6P·2C7H17NO5 分子量 1004.84
纯度 98% 配送 惯例下常温包邮
产品描述 Fosaprepitant Dimeglumine is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis.
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