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CAS号 | 290297-26-6 | 货号 | BCP08751 |
中文名 | 奈妥吡坦 | ||
英文名 | Netupitant | ||
中文别名 | |||
英文别名 | Ro 67-3189; Ro-67-3189; Ro67-3189; Ro-673189000;CID6451149; CID 6451149; CID-6451149; | ||
SMILES | CN1CCN(C2=CC(C3=C(C)C=CC=C3)=C(N(C)C(C(C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)(C)C)=O)C=N2)CC1 | ||
化学名称 | |||
分子式 | C30H32F6N4O | 分子量 | 578.59 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the activity of the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV). |
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