LMP744 hydrochloride 新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP34016CAS号：308246-57-3纯度：98%

规格	价格(CNY)	是否现货	购买咨询
10.00 mg	￥1600.00	In-stock	购买咨询
25.00 mg	￥2200.00	In-stock	购买咨询
50.00 mg	￥3200.00	In-stock	购买咨询

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CAS号	308246-57-3	货号	BCP34016
中文名	LMP744 hydrochloride
英文名	LMP744 hydrochloride
中文别名
英文别名	LMP-744 hydrochloride; LMP-744 HCl; LMP744 HCl; LMP 744 HCl;MJ-III65 hydrochloride; NSC706744 hydrochloride;
SMILES	COC1=C(C=C2C(=C1)C3=C(C4=CC5=C(C=C4C3=O)OCO5)N(C2=O)CCCNCCO)OC.Cl
化学名称
分子式	C24H25ClN2O7	分子量	488.92
纯度	98%	配送	惯例下常温包邮
产品描述	LMP-744 hydrochloride is a DNA intercalator and topoisomerase inhibitor with antitumor activity. LMP-744 HCl produces persistent topoisomerase I cleavage complexes and overcome multidrug resistance. Consistent with Top1 poisoning, protein-linked DNA breaks were detected in cells treated with LMP-744 HCl at nanomolar concentrations. Studies in human cells in culture found LMP-744 HCl to be cytotoxic. Furthermore, limited cross-resistance was observed in camptothecin-resistant cell lines. LMP-744 HCl also exhibits antitumor activity in mouse tumor xenografts.