苦鬼臼素新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP18482CAS号：477-47-4纯度：98%

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CAS号	477-47-4	货号	BCP18482
中文名	苦鬼臼素
英文名	Picropodophyllin
中文别名	苦鬼臼脂素;
英文别名	(-)PPP;AXL1717; AXL-1717; AXL 1717; PPP; Picropodophyllotoxin;
SMILES
化学名称
分子式	C22H22O8	分子量	414.41
纯度	98%	配送	惯例下常温包邮
产品描述	AXL1717, also known as Picropodophyllotoxin, Picropodophyllin or PPP, is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential antineoplastic activity. Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors, such as receptors for insulin, epidermal growth factor, platelet-derived growth factor, fibroblast growth factor and mast/stem cell growth factor (KIT). This agent shows potent activity in the suppression o f tumor cell proliferation and the induction of tumor cell apoptosis.

苦鬼臼素 新