沃替西汀新热

参考资料仅供科学研究，不可用于个人用途。

货号：BCP05996CAS号：508233-74-7纯度：98%

在线咨询

购买咨询

全国免运费！免费咨询：400-099-8200 或手机联系：13472751340

* 必填项

请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。

* Required Fields.

Please complete the form below and we will contact you shortly.

* Required Fields.

Please complete the form below and we will contact you shortly.

CAS号	508233-74-7	货号	BCP05996
关联产品	960203-27-4（沃替西汀氢溴酸盐）
中文名	沃替西汀
英文名	Vortioxetine
中文别名
英文别名	Lu AA 21004；LuAA21004； Lu-AA21004； Lu AA21004； AA21004; AA-21004; AA 21004;
SMILES
化学名称
分子式	C18H22N2S	分子量	298.45
纯度	98%	配送	惯例下常温包邮
产品描述	Vortioxetine, also known as Lu AA21004, is an atypical antidepressant, and was approved in 2013 by the U.S. FDA for the treatment of major depressive disorder (MDD) in adults. Vortioxetine is a so-called "serotonin modulator and stimulator." It has been shown to possess the following pharmacological actions: Serotonin transporter (SERT) blocker (i.e. serotonin reuptake inhibitor (SRI)) — Ki (binding affinity) = 1.6 nM, IC50 = 5.4 nM; Norepinephrine transporter (NET) blocker — Ki = 113 nM; 5-HT1A receptor high-efficacy partial agonist/near-full agonist — Ki = 15 nM, IA = 80%; 5-HT1B receptor partial agonist — Ki = 33 nM; 5-HT1D receptor antagonist — Ki = 54 nM; 5-HT3A receptor antagonist — Ki = 3.7 nM; 5-HT7 receptor antagonist — Ki = 19 nM.

沃替西汀 新 热