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| CAS号 | 625115-52-8 | 货号 | BCP16721 |
| 中文名 | Nelociguat | ||
| 英文名 | Nelociguat | ||
| 中文别名 | |||
| 英文别名 | BAY60-4552; BAY 60-4552; BAY-60-4552; BAY604552; BAY-604552; BAY 604552; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C19H17FN8O2 | 分子量 | 408.39 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Nelociguat, also known as BAY60-4552, is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway. On binding of NO to its prosthetic haem group, sGC catalyses the synthesis of the second messenger cyclic guanosine monophosphate (cGMP), which promotes vasodilation and inhibits smooth muscle proliferation, leukocyte recruitment, platelet aggregation and vascular remodelling through a number of downstream mechanisms. | ||
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