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| CAS号 | 898537-18-3 | 货号 | BCP20937 |
| 中文名 | 鲁格列净 | ||
| 英文名 | Luseogliflozin | ||
| 中文别名 | |||
| 英文别名 | TS-71; TS 71; TS71; TS-071; TS 071; TS071; | ||
| SMILES | CCOC1=CC=C(C=C1)CC2=C(C=C(C(=C2)C3C(C(C(C(S3)CO)O)O)O)OC)C | ||
| 化学名称 | |||
| 分子式 | C23H30O6S | 分子量 | 434.54 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Luseogliflozin, also known as TS-71 and TS-071, is a potent and competitive inhibitor of sodium-dependent glucose cotransporter 2 (SGLT2 inhibitor). Luseogliflozin improves glycaemic control assessed by continuous glucose monitoring even on a low-carbohydrate diet. Luseogliflozin competitively inhibited human SGLT2 (hSGLT2)-mediated glucose uptake with a Ki value of 1.10 nM. In the absence of glucose, [(3)H]-luseogliflozin exhibited a high affinity for hSGLT2 with a Kd value of 1.3 nM. | ||
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