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CAS号 | 899713-86-1 | 货号 | BCP18861 |
中文名 | ML 348 | ||
英文名 | ML 348 | ||
中文别名 | |||
英文别名 | ML-348;ML348; CID 3238952; SID 160654487; CID3238952; SID160654487; | ||
SMILES | |||
化学名称 | |||
分子式 | C18H17ClF3N3O3 | 分子量 | 415.79 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | ML348, also known as CID 3238952; SID 160654487, is a reversible LYPLA1 inhibitor with an IC50 value of 210 nM. Multiple oncogenes, including HRAS and SRC, require palmitoylation for malignant transformation. Lysophospholipase 1 (LYPLA1) has been identified as a candidate protein palmitoyl thioesterase responsible for HRAS depalmitoylation in mammalian cells. |
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