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CAS号 | 928774-43-0 | 货号 | BCP02331 |
中文名 | PF-3716556 | ||
英文名 | PF-3716556 | ||
中文别名 | |||
英文别名 | PF3716556;PF-03716556;PF 03716556; | ||
SMILES | |||
化学名称 | |||
分子式 | C22H26N4O3 | 分子量 | 394.47 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | PF-03716556 is a potent, and selective acid pump antagonist with pIC50 of about of 6.026 and 7.095 for the inhibition of porcine H+,K+-ATPase activity in ion-leaky and ion-tight assay, respectively. PF-03716556 is used for the treatment of gastroesophageal reflux disease. PF-03716556 is highly selective for H+, K+-ATPase in vitro, displays no activity at Na+, K+-ATPase. PF-03716556 has no species differences among the porcine, canine and human enzymes. PF-03716556 has a competitive and reversible mode of action. |
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