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SB1317 结构式

SB1317

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP07033CAS号 :937270-47-8纯度:98%
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  • 基本信息与产品描述
CAS号 937270-47-8 货号 BCP07033
关联产品 1204918-72-8(SB 1317)
中文名 SB1317
英文名 SB1317
中文别名
英文别名 TG02; SB 1317; TG 02; SB-1317; TG-02;
SMILES
化学名称
分子式 C23H24N4O 分子量 372.46
纯度 98% 配送 惯例下常温包邮
产品描述 TG02, also known as SB1317, is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. It dose-dependently inhibits signaling pathways downstream of CDKs, JAK2 and FLT3 in cancer cells with the main targets being CDKs. TG02 is anti-proliferative in a broad range of tumor cell lines, inducing G1 cell cycle arrest and apoptosis. In vivo, TG02 exhibits favorable pharmacokinetics after oral dosing in xenograft models and accumulates in tumor tissues, inducing an effective blockade of both CDK and S
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