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| CAS号 | 959850-74-9 | 货号 | BCP46589 |
| 中文名 | AP1189 acetate | ||
| 英文名 | AP1189 acetate | ||
| 中文别名 | |||
| 英文别名 | AP 1189 acetate;AP-1189 acetate; | ||
| SMILES | NC(N/N=C/C=C/C1=CC=CN1C2=CC=CC=C2[N+]([O-])=O)=N.CC(O)=O | ||
| 化学名称 | |||
| 分子式 | C16H18N6O4 | 分子量 | 358.36 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | AP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages. No melanogenesis was induced by AP1189 in B16-F10 melanocytes. In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ∼3-fold. | ||
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