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CAS号 | 960374-59-8 | 货号 | BCP07652 |
中文名 | ONX-0914 | ||
英文名 | ONX-0914 | ||
中文别名 | |||
英文别名 | PR957; PR-957; PR 957; ONX0914; ONX 0914; | ||
SMILES | |||
化学名称 | |||
分子式 | C31H40N4O7 | 分子量 | 580.67 |
纯度 | 95% | 配送 | 惯例下常温包邮 |
产品描述 | ONX 0914 is an immunoproteasome inhibitor with potential treatment applications in autoimmune disorders, such as rheumatoid arthritis, inflammatory bowel disease and lupus. ONX 0914 was designed to be a potent inhibitor of the immunoproteasome with minimal cross-reactivity for the constitutive proteasome. Recent evidence suggests that the immunoproteasome regulates the production of several inflammatory cytokines, including Tumor Necrosis Factor-α (TNF-α), Interleukin-6 (IL-6), IL-17, and IL- |
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