雷罗他非新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP46999CAS号：1008510-37-9纯度：98%

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CAS号	1008510-37-9	货号	BCP46999
关联产品	1809275-69-1（Razuprotafib sodium）
中文名	雷罗他非
英文名	Razuprotafib
中文别名
英文别名	AKB-9778; AKB 9778; AKB9778;
SMILES	COC(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC2=CC=C(C=C2)NS(=O)(=O)O)C3=CSC(=N3)C4=CC=CS4
化学名称
分子式	C26H26N4O6S3	分子量	586.7
纯度	98%	配送	惯例下常温包邮
产品描述	Razuprotafib is a small molecule inhibitor of vascular endothelial protein tyrosine phosphatase (VE-PTP), with potential vasculature stabilizing activity. Upon administration, razuprotafib targets, binds to and inhibits VE-PTP, which is a negative regulator of the endothelial cell (EC)-specific receptor tyrosine kinase (RTK) Tie2. This restores Tie2 activation, which may improve endothelial function and stabilize blood vessels. VE-PTP is upregulated in stressed endothelium associated with a variety of diseases. Tie2 plays an important role in endothelial function and vascular stability. A decrease in Tie2 activation leads to vascular leakage and inflammation.

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