参考资料
在线咨询
购买咨询即时询价 ×
* 必填项
请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS号 | 1073160-26-5 | 货号 | BCP17737 |
| 关联产品 | 1073154-85-4（地法替尼） 1345713-71-4（地法替尼） | ||
| 中文名 | 地法替尼盐酸盐 | ||
| 英文名 | Defactinib hydrochloride | ||
| 中文别名 | |||
| 英文别名 | PF-04554878 hydrochloride;PF04554878 hydrochloride;PF 04554878 hydrochloride;VS6063 hydrochloride;VS 6063 hydrochloride;VS6063 hydrochloride; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C20H22ClF3N8O3S | 分子量 | 546.95 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | VS-6063 inhibited FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner. The combination of VS-6063 and paclitaxel markedly decreased proliferation and increased apoptosis, which resulted in 92.7% to 97.9% reductions in tumor weight. RPPA data showed that VS-6063 reduced levels of AKT and YB-1 in taxane-resistant cell lines. FAK inhibition enhanced chemosensitivity in taxane-resistant cells by decreasing YB-1 phosphorylation and subsequently CD44 in an AKT-dependent manner. | ||
在购买和使用瀚香生物产品的过程中，您遇到的任何问题，都可以咨询我们的免费热线：400-099-8200，或者和我们的客服 
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。
Tags:Defactinib hydrochloride 供应商,Defactinib hydrochloride 购买,Defactinib hydrochloride 生产,Defactinib hydrochloride 批量,Defactinib hydrochloride 供应,Defactinib hydrochloride 订购,Defactinib hydrochloride 采购