1-甲基-D-色氨酸

参考资料仅供科学研究，不可用于个人用途。

货号：BCP08015CAS号：110117-83-4纯度：98%

在线咨询

购买咨询

全国免运费！免费咨询：400-099-8200 或手机联系：13472751340

* 必填项

请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。

* Required Fields.

Please complete the form below and we will contact you shortly.

* Required Fields.

Please complete the form below and we will contact you shortly.

CAS号	110117-83-4	货号	BCP08015
中文名	1-甲基-D-色氨酸
英文名	Indoximod
中文别名
英文别名	NLG-8189;NLG 8189;NLG8189;1-Methyl-D-tryptophan;
SMILES
化学名称
分子式	C12H14N2O2	分子量	218.25
纯度	98%	配送	惯例下常温包邮
产品描述	1-Methyl-D-tryptophan is an inhibitor of the enzymes IDO and INDOL1 (indolamine 2,3-dioxygenase 1 and 2) with selectivity for INDOL1. The enzymes perform similar transformations and are responsible for catalyzing the rate-limiting step of oxidative tryptophan catabolism in the kynurenine pathway. IDO activity is correlated with an induction of tolerance and immunosuppresion through activation of regulatory T cells by metabolites generated from tryptophan catabolism. Inhibition of IDO by 1-Methyl-D-tryptophan blocks this induced immune suppression, which has shown utility in suppressing acquired immunities of tumors and indicates potential for chemical intervention of chronic inflammatory diseases.